As the threats from cyberspace to IT systems (information technology) and digital OT systems (operational technologies) using ICT technologies (information and communication technologies) grow exponentially, while at the same time the scale of the use of digital data collecting, processing and sharing for the needs of many national economy areas and to support functioning of the state in terms of, for example, defence, health care, education or citizen services, building awareness of the risks and skills to secure networks, systems and digital services against cyber threats becomes crucial. A new type of structures called ISACs (Information Sharing and Analysis Centres) play an important role in this respect. The co-authors, based on the provisions of the law and their own experience in ISAC-Kolej and ISAC-GIG centers, present the ecosystem around ISAC centers, their tasks and challenges.